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Comparação de pesquisa

CJC-1295 vs Ipamorelin

CJC-1295 (with DAC) is a 30-residue modified GRF(1-29) analog carrying an albumin-binding DAC group, characterized at the GHRH receptor. Ipamorelin is a 5-residue synthetic peptide (Aib, D-2-Nal, D-Phe) characterized at GHSR-1a. They differ in receptor class, length, and molecular weight (3647.2 vs 711.9 g/mol).

CJC-1295

Modified GRF(1-29) analog with an albumin-binding DAC group; 30 residues.

Ipamorelin

Synthetic pentapeptide (Aib, D-2-Nal, D-Phe) with a C-terminal amide.

AtributoCJC-1295Ipamorelin
Peptide class / structureGHRH analog — modified GRF(1-29) with an albumin-binding DAC groupSynthetic pentapeptide (Aib, D-2-Nal, D-Phe); C-terminal amide
Receptor class (binding assays)GHRH receptorGH secretagogue receptor (GHSR-1a)
Length (residues)30 aa5 aa
Molecular formulaC165H269N47O46C38H49N9O5
Molecular weight3647.2 g/mol711.9 g/mol
CAS number446262-90-4170851-70-4
Supplied asLyophilized powder, 5 mg vialLyophilized powder, 5 mg vial
COA on fileNot yetYes (Freedom Diagnostics Testing)

Perguntas frequentes

What is the main structural difference between CJC-1295 and Ipamorelin?+

CJC-1295 (with DAC) is a 30-residue GHRH analog — GRF(1-29) modified with an albumin-binding DAC group (C165H269N47O46). Ipamorelin is a 5-residue peptide built with the non-standard residues Aib, D-2-Nal and D-Phe and a C-terminal amide (C38H49N9O5). They are ligands for different receptor classes rather than variants of one sequence.

How do their molecular weights compare?+

CJC-1295 (with DAC) is 3647.2 g/mol and Ipamorelin is 711.9 g/mol. Both are free-base figures; peptides are commonly supplied as acetate or TFA salts, so the exact species and net peptide content of a lot are reported on its Certificate of Analysis.

Is the CJC-1295 in the CJC-1295 + Ipamorelin blend the with-DAC compound?+

No. The CJC-1295 wo DAC + Ipamorelin blend (5 mg / 5 mg) uses CJC-1295 without DAC, CAS 863288-34-0. The single-compound CJC-1295 listing compared here is the with-DAC compound, CAS 446262-90-4.

Can CJC-1295 and Ipamorelin be studied together?+

They are ligands for different receptor classes (GHRH receptor vs GHSR-1a), so in-vitro receptor-signaling work sometimes includes both. For a single vial, see the CJC-1295 wo DAC + Ipamorelin blend, which uses the no-DAC form of CJC-1295.

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