Para uso exclusivo em pesquisa laboratorial. Não destinado ao consumo humano. Não destinado a uso clínico ou terapêutico. Não avaliado pela FDA.
Comparação de pesquisa
Ipamorelin vs Tesamorelin
Ipamorelin and Tesamorelin are ligands for different receptor classes and differ greatly in size. Ipamorelin is a 5-residue synthetic peptide (Aib, D-2-Nal, D-Phe) characterized at GHSR-1a, at 711.9 g/mol. Tesamorelin is a 44-residue GHRH(1-44) analog with an N-terminal trans-3-hexenoyl cap, characterized at the GHRH receptor, at 5135.9 g/mol.
Tesamorelin
GHRH(1-44) analog with an N-terminal trans-3-hexenoyl cap; 44 residues.
| Atributo | Ipamorelin | Tesamorelin |
|---|---|---|
| Peptide class / structure | Synthetic pentapeptide (Aib, D-2-Nal, D-Phe) | GHRH(1-44) analog |
| Receptor class (binding assays) | GH secretagogue receptor (GHSR-1a) | GHRH receptor |
| Terminal modifications | C-terminal amide | N-terminal trans-3-hexenoyl cap; C-terminal amide |
| Length (residues) | 5 aa | 44 aa |
| Molecular formula | C38H49N9O5 | C221H366N72O67S |
| Molecular weight | 711.9 g/mol | 5135.9 g/mol |
| CAS number | 170851-70-4 | 218949-48-5 |
| Supplied as | Lyophilized powder, 5 mg vial | Lyophilized powder, 5 mg vial |
| COA on file | Yes (Freedom Diagnostics Testing) | Yes (Kovera Labs) |
Perguntas frequentes
Is Tesamorelin in the same receptor class as Ipamorelin?+
No. Tesamorelin is a GHRH(1-44) analog characterized at the GHRH receptor, while Ipamorelin is a short synthetic peptide characterized at GHSR-1a. They are ligands for two different receptors rather than two versions of one compound.
How do their sizes compare?+
Ipamorelin is 5 residues (C38H49N9O5, 711.9 g/mol); Tesamorelin is 44 residues (C221H366N72O67S, 5135.9 g/mol). Both are free-base figures; the salt form and net peptide content of a specific lot are reported on its Certificate of Analysis.
Are both supplied lyophilized?+
Yes — both are supplied as lyophilized powder. Store unopened vials at −20 °C for the long term, protected from light and moisture; aliquoting avoids repeated freeze–thaw once in solution.