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Glucagon Receptor

Também conhecido como: GCGR

The glucagon receptor (GCGR) is a class B G protein-coupled receptor for the hormone glucagon that signals primarily through the Gs/cAMP pathway.

GCGR is a close structural relative of the incretin receptors and shares their Gs/adenylyl-cyclase/cAMP output; in some cell backgrounds it also couples to Gq-linked calcium signaling. It is studied most often in hepatocyte-derived models.

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