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Base de conocimientos

Blog de investigación

Recursos educativos sobre ciencia de péptidos, control de calidad, buenas prácticas de almacenamiento y fundamentos de laboratorio. Escritos para investigadores, por investigadores.

8 min de lectura

What Is IGF-1? Insulin-Like Growth Factor Explained

IGF-1 for researchers: the GH–IGF-1 axis, the IGF-1 receptor and PI3K/Akt signaling, binding proteins, and the IGF-1 LR3 analog. Research use only.

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7 min de lectura

IGF-1 LR3 vs Native IGF-1: What the R3 Substitution Changes

IGF-1 LR3 vs native IGF-1: the R3 substitution, reduced IGF-binding-protein affinity, free fraction, and receptor potency. Research use only.

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7 min de lectura

Peptide Sciences Alternative: How to Vet a New Supplier

Peptide Sciences closed March 6, 2026. A guide to vetting a Peptide Sciences alternative on COA quality, HPLC and mass-spec testing, and US shipping.

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6 min de lectura

Science.bio Alternative: How to Vet a Research Supplier

Science.bio shut down around January 2026. A guide to vetting a Science.bio alternative on third-party COAs, HPLC and mass-spec purity, and US shipping.

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6 min de lectura

Amino Asylum Alternative: A Research Sourcing Guide

Amino Asylum went defunct in 2025. A sourcing-continuity guide to vetting an Amino Asylum alternative on COA quality, testing, and US shipping.

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8 min de lectura

Research-Peptide Vendor Shutdowns 2025-2026: Sourcing Guide

Amino Asylum, Science.bio, and Peptide Sciences all shut down in 2025-2026. A rubric for vetting any research-peptide supplier on testing and logistics.

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7 min de lectura

How to Read a Certificate of Analysis (COA)

Learn what a Certificate of Analysis contains, how to interpret HPLC and mass spectrometry data, and what separates a legitimate COA from a fabricated one.

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5 min de lectura

The Complete Guide to Peptide Storage

How to store research peptides: lyophilized versus reconstituted storage, temperature guidelines, freeze-thaw limits, and shelf-life expectations.

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7 min de lectura

What Are Research Peptides? A Beginner's Guide

An introduction to research peptides: what they are, how they are synthesized, the common categories, and why purity governs reliable results.

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8 min de lectura

BPC-157: A Comprehensive Research Overview

BPC-157, a synthetic pentadecapeptide derived from gastric juice: its structure, molecular weight, proposed mechanisms, and preclinical context.

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5 min de lectura

Ipamorelin: Research Applications and Handling

Ipamorelin, a selective growth hormone secretagogue: its GHSR-1a binding profile, preclinical research areas, and laboratory handling and storage.

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5 min de lectura

CJC-1295: DAC vs No DAC — Key Differences for Researchers

CJC-1295 with DAC versus without DAC (Modified GRF 1-29): the albumin-binding chemistry, duration differences, and how each suits a study design.

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5 min de lectura

GHK-Cu: Copper Peptide Research and Applications

GHK-Cu, a naturally occurring copper-binding tripeptide: copper coordination, gene-expression modulation, matrix remodeling, and antioxidant assays.

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5 min de lectura

Selank: Neuropeptide Research Overview

Selank, a synthetic tuftsin analog: its Pro-Gly-Pro stabilizing extension, BDNF and monoamine signaling, and immune-regulatory properties.

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5 min de lectura

Semax: ACTH(4-7) Peptide Research Applications

Semax, an ACTH(4-7) derivative studied in preclinical models for CNS signaling, BDNF and NGF modulation, and neuroprotective mechanisms.

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5 min de lectura

NAD+: Nicotinamide Adenine Dinucleotide in Cell Research

NAD+ in cellular research: its role as a redox cofactor, sirtuin and PARP substrate, mitochondrial function, and age-related decline in models.

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5 min de lectura

TB-500 (Thymosin Beta-4): Research Applications

TB-500, a synthetic fragment of thymosin beta-4: the LKKTETQ actin-binding motif, cell-migration assays, and angiogenesis research models.

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4 min de lectura

PT-141: Melanocortin Receptor Research

PT-141, a synthetic melanocortin receptor agonist: MC3R and MC4R binding affinity, CNS signaling studies, and melanocortin system pharmacology.

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5 min de lectura

What is HPLC Testing? Understanding Peptide Purity Analysis

How High-Performance Liquid Chromatography measures peptide purity, how to read a chromatogram, and which method parameters a COA should report.

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5 min de lectura

How Research Peptides Are Synthesized: SPPS Explained

Solid-Phase Peptide Synthesis explained: resin supports, protecting groups, coupling chemistry, TFA cleavage, and preparative HPLC purification.

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4 min de lectura

What to Look for in a Research Peptide Supplier

How to evaluate a research peptide supplier: Certificate of Analysis standards, third-party testing, cold-chain storage, and common red flags.

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4 min de lectura

How to Reconstitute Lyophilized Peptides for Research

How to reconstitute lyophilized research peptides: solvent selection, correct technique, concentration calculation, and post-reconstitution storage.

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4 min de lectura

Peptide Purity Grades: Research vs Pharmaceutical

Peptide purity grades explained: what a purity percentage measures, how research-grade and GMP material differ, and the testing behind each tier.

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5 min de lectura

IGF-1 LR3: Extended Half-Life Growth Factor Research

IGF-1 LR3, a modified insulin-like growth factor: the R3 substitution and Long extension, cell-culture applications, and laboratory handling.

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6 min de lectura

Tesamorelin: GRF Analog Research Overview

Tesamorelin, a synthetic analog of growth hormone releasing factor (GRF 1-44): its structure, GHRH receptor binding, and GH axis research use.

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6 min de lectura

MOTS-c: Mitochondrial-Derived Peptide Research

MOTS-c, a peptide encoded by the mitochondrial genome: its discovery, AMPK activation mechanism, and role in cellular metabolism research.

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5 min de lectura

Bacteriostatic Water: Composition, Storage, and Lab Use

Bacteriostatic water for research use: its 0.9% benzyl alcohol composition, preservative mechanism, storage, and how it differs from sterile water.

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6 min de lectura

MT-2: Melanocortin Receptor Research Applications

MT-2, a synthetic cyclic lactam analog of alpha-MSH: MC1R binding, melanocortin receptor pharmacology, and reference-ligand applications.

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6 min de lectura

Peptide Degradation: Causes and Key Risk Factors

What degrades research peptides: temperature, light, moisture, oxidation, and freeze-thaw cycles, plus practical steps for preserving purity.

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6 min de lectura

How to Verify Peptide Quality Before Use in Research

How to verify peptide quality before use: reading a COA, assessing HPLC chromatograms, confirming identity by mass spectrometry, and red flags.

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6 min de lectura

Peptide Solubility: Choosing the Right Solvent for Research

Choosing a peptide solvent: when to use bacteriostatic water, DMSO, dilute acetic acid, or PBS, and how sequence properties drive solubility.

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7 min de lectura

CJC-1295 vs Ipamorelin vs Tesamorelin: GH Secretagogues

CJC-1295, Ipamorelin, and Tesamorelin compared: their receptor targets, duration profiles, and which suits a given preclinical study design.

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6 min de lectura

What Is Lyophilization? Understanding Freeze-Dried Peptides

Lyophilization explained: the freezing, sublimation, and desorption stages, why peptides are freeze-dried, and how to reconstitute the powder.

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