Только для использования в лабораторных исследованиях. Не для употребления человеком. Не для клинического или терапевтического применения. Не оценивалось FDA.
Исследовательское сравнение
Ipamorelin vs Tesamorelin
Ipamorelin and Tesamorelin are ligands for different receptor classes and differ greatly in size. Ipamorelin is a 5-residue synthetic peptide (Aib, D-2-Nal, D-Phe) characterized at GHSR-1a, at 711.9 g/mol. Tesamorelin is a 44-residue GHRH(1-44) analog with an N-terminal trans-3-hexenoyl cap, characterized at the GHRH receptor, at 5135.9 g/mol.
Tesamorelin
GHRH(1-44) analog with an N-terminal trans-3-hexenoyl cap; 44 residues.
| Параметр | Ipamorelin | Tesamorelin |
|---|---|---|
| Peptide class / structure | Synthetic pentapeptide (Aib, D-2-Nal, D-Phe) | GHRH(1-44) analog |
| Receptor class (binding assays) | GH secretagogue receptor (GHSR-1a) | GHRH receptor |
| Terminal modifications | C-terminal amide | N-terminal trans-3-hexenoyl cap; C-terminal amide |
| Length (residues) | 5 aa | 44 aa |
| Molecular formula | C38H49N9O5 | C221H366N72O67S |
| Molecular weight | 711.9 g/mol | 5135.9 g/mol |
| CAS number | 170851-70-4 | 218949-48-5 |
| Supplied as | Lyophilized powder, 5 mg vial | Lyophilized powder, 5 mg vial |
| COA on file | Yes (Freedom Diagnostics Testing) | Yes (Kovera Labs) |
Часто задаваемые вопросы
Is Tesamorelin in the same receptor class as Ipamorelin?+
No. Tesamorelin is a GHRH(1-44) analog characterized at the GHRH receptor, while Ipamorelin is a short synthetic peptide characterized at GHSR-1a. They are ligands for two different receptors rather than two versions of one compound.
How do their sizes compare?+
Ipamorelin is 5 residues (C38H49N9O5, 711.9 g/mol); Tesamorelin is 44 residues (C221H366N72O67S, 5135.9 g/mol). Both are free-base figures; the salt form and net peptide content of a specific lot are reported on its Certificate of Analysis.
Are both supplied lyophilized?+
Yes — both are supplied as lyophilized powder. Store unopened vials at −20 °C for the long term, protected from light and moisture; aliquoting avoids repeated freeze–thaw once in solution.