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Research Comparison

GHRP-2 vs GHRP-6

GHRP-2 and GHRP-6 are both synthetic hexapeptides that contain D-amino acids and end in a C-terminal amide. They differ in sequence and composition: GHRP-6 is His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂ (C46H56N12O6, 873.0 g/mol), while GHRP-2 is C45H55N9O6 at 818.0 g/mol. Both are supplied as lyophilized powder.

GHRP-2

Synthetic hexapeptide with D-amino acids; C-terminal amide.

GHRP-6

Synthetic hexapeptide (His-D-Trp-Ala-Trp-D-Phe-Lys); C-terminal amide.

AttributeGHRP-2GHRP-6
Peptide class / structureSynthetic hexapeptide containing D-amino acids; C-terminal amideSynthetic hexapeptide: His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂
Receptor class (binding assays)GH secretagogue receptor (GHSR-1a)GH secretagogue receptor (GHSR-1a)
Length (residues)6 aa6 aa
Molecular formulaC45H55N9O6C46H56N12O6
Molecular weight818.0 g/mol873.0 g/mol
CAS number158861-67-787616-84-0
Supplied asLyophilized powder, 10 mg vialLyophilized powder, 10 mg vial
COA on fileNot yetNot yet

Frequently Asked Questions

How do GHRP-2 and GHRP-6 differ chemically?+

Both are six-residue synthetic peptides with D-amino acids and a C-terminal amide, but their sequences differ. GHRP-6 is His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂ (C46H56N12O6, CAS 87616-84-0); GHRP-2 is C45H55N9O6 (CAS 158861-67-7). GHRP-6 carries three more nitrogen atoms than GHRP-2.

How do their molecular weights compare?+

GHRP-2 is 818.0 g/mol and GHRP-6 is 873.0 g/mol. These are free-base values; peptides like these are commonly supplied as acetate or TFA salts, which weigh more, so the exact species and net peptide content of a lot belong on its Certificate of Analysis.

Are both supplied lyophilized?+

Yes — both are supplied as lyophilized powder. Store unopened vials at −20 °C for the long term (2–8 °C short term), protected from light and moisture, and avoid repeated freeze–thaw once in solution.

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