For laboratory research use only. Not for human consumption. Not for clinical or therapeutic use. Not evaluated by the FDA.
For laboratory research use only. Not for human consumption. Not for clinical or therapeutic use. Not evaluated by the FDA.
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A synthetic analog of insulin-like growth factor with an extended activity profile due to the arginine substitution at position 3. Used exclusively in preclinical in-vitro research to study receptor binding kinetics and downstream signaling pathways.
Dosage
1mg
Purity
99.1%
Form
Lyophilized Powder
Third-Party Tested
HPLC & mass-spec verified · every batch
Every batch is independently verified by HPLC and mass spectrometry to 99.1% purity and ships with a lot-specific Certificate of Analysis.
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$49.95
Research Application Guidelines
This research compound is designed exclusively for controlled in vitro studies carried out by trained professionals. It is not intended for human or animal use and must not be incorporated into foods, cosmetics, medications, or diagnostic processes.
Regulatory Notice
This material has not been evaluated by the FDA and is not sold for the purpose of diagnosing, treating, curing, or preventing any condition. All handling, storage, and research use must comply with applicable regulations and institutional requirements.
Purchase & Responsibility Agreement
By purchasing from Ascension Labs, the buyer confirms that they are a qualified researcher or authorized laboratory. All sales are final. The buyer assumes full responsibility for the proper handling, storage, usage, and regulatory compliance of this material.
What's Included
Storage Guidelines
Quality Assurance
Disclaimer: Our peptides are research-grade products for laboratory use only. They are not approved for human consumption or medical use. Always follow proper laboratory safety protocols.
IGF-1 LR3 is a synthetic insulin-like growth factor analog with an arginine substitution at position 3 for an extended activity profile. It is studied in vitro for receptor binding kinetics and downstream signaling.
Also referred to as: IGF-1 LR3, Long R3 IGF-1, IGF1 LR3, Insulin-like growth factor 1 (IGF-1), somatomedin C.
IGF-1 LR3 is an analog of insulin-like growth factor-1 studied as an agonist at the IGF-1 receptor. In cell-based assays, receptor binding activates downstream PI3K/Akt signaling, which researchers link to proliferation and differentiation readouts. Binding-kinetics studies characterize its receptor engagement, all within cultured, non-human models focused on IGF-1 pathway mechanisms.
IGF-1 LR3 (Long R3 IGF-1) is an 83-amino-acid analog of human IGF-1. It combines an arginine substitution at position 3 with a 13-residue N-terminal extension. These modifications reduce binding to IGF-binding proteins, extending its activity in research. It is characterized structurally by this extended, substituted sequence rather than by native IGF-1's.
Native IGF-1 binds tightly to IGF-binding proteins, which limits its free activity. IGF-1 LR3 carries an Arg3 substitution and an N-terminal extension that sharply reduce this binding-protein affinity, leaving more peptide available to engage the receptor in vitro. Comparative studies use this to examine prolonged, less-buffered IGF-1-receptor signaling.
Yes. Every batch of IGF-1 LR3 is independently tested by HPLC and mass spectrometry, and ships with a lot-specific Certificate of Analysis verifying 99.1% purity and molecular identity.
Store lyophilized IGF-1 LR3 at -20°C for long-term storage or 2-8°C short-term. After reconstitution, keep refrigerated at 2-8°C and avoid repeated freeze-thaw cycles.
No. IGF-1 LR3 is sold strictly for in-vitro research and laboratory use only. It is not a drug or supplement and is not intended for human or animal consumption.