For laboratory research use only. Not for human consumption. Not for clinical or therapeutic use. Not evaluated by the FDA.
For laboratory research use only. Not for human consumption. Not for clinical or therapeutic use. Not evaluated by the FDA.
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A mitochondrial-derived peptide encoded within the 12S rRNA gene of the mitochondrial genome. Investigated in preclinical research for its role in mitochondrial signaling, AMPK pathway activation, and cellular metabolic regulation in in-vitro and animal model studies.
Dosage
10mg
Purity
99.2%
Form
Lyophilized Powder
Third-Party Tested
Janoshik Analytical · April 2026
Verified Purity
99.2%
Verification Key
14L4VGBU76ZY
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Research Application Guidelines
This research compound is designed exclusively for controlled in vitro studies carried out by trained professionals. It is not intended for human or animal use and must not be incorporated into foods, cosmetics, medications, or diagnostic processes.
Regulatory Notice
This material has not been evaluated by the FDA and is not sold for the purpose of diagnosing, treating, curing, or preventing any condition. All handling, storage, and research use must comply with applicable regulations and institutional requirements.
Purchase & Responsibility Agreement
By purchasing from Ascension Labs, the buyer confirms that they are a qualified researcher or authorized laboratory. All sales are final. The buyer assumes full responsibility for the proper handling, storage, usage, and regulatory compliance of this material.
What's Included
Storage Guidelines
Quality Assurance
Disclaimer: Our peptides are research-grade products for laboratory use only. They are not approved for human consumption or medical use. Always follow proper laboratory safety protocols.
MOTS-c is a mitochondrial-derived peptide encoded within the 12S rRNA gene. It is studied for mitochondrial signaling, AMPK-pathway activation, and cellular metabolic regulation.
Also referred to as: MOTSc, mitochondrial open reading frame peptide, MOTS-c peptide.
MOTS-c is a mitochondrial-derived peptide of 16 amino acids, encoded within the 12S ribosomal RNA (MT-RNR1) region of mitochondrial DNA rather than the nuclear genome. This unusual origin defines its class as a mitochondrial-derived signaling peptide, and it is characterized in research by its short 16-residue sequence and mitochondrial genomic source.
In cellular research, MOTS-c is investigated for mitochondrial-to-nuclear retrograde signaling, activation of the AMPK metabolic pathway, and broader regulation of cellular energy metabolism. Studies examine how this peptide relays mitochondrial status to influence nuclear gene programs. These roles are characterized in vitro and in animal models as preclinical metabolic-signaling mechanisms.
MOTS-c is supplied as a lyophilized powder, stored dry, cold, and protected from light to preserve the peptide. In research it serves as a tool for probing mitochondrial signaling and cellular metabolic-regulation pathways. Prepared solutions are kept cold and used promptly, and repeated freeze-thaw cycles are minimized to maintain the peptide's integrity.
Yes. Every batch of MOTS-c is independently tested by HPLC and mass spectrometry, and ships with a lot-specific Certificate of Analysis verifying 99.2% purity and molecular identity.
Store lyophilized MOTS-c at -20°C for long-term storage or 2-8°C short-term. After reconstitution, keep refrigerated at 2-8°C and avoid repeated freeze-thaw cycles.
No. MOTS-c is sold strictly for in-vitro research and laboratory use only. It is not a drug or supplement and is not intended for human or animal consumption.